Non-Hodgkin's Lymphoma

Approximately, 9 in 1 million children under the age of 15 years will develop Non-Hodgkin's Lymphoma each year. 55% of childhood lymphomas are Non-Hodgkin's Lymphomas.

It is known that environmental toxins such as pesticides can cause lymphoma. Scientists also believe that viruses and bacteria can play a role in contracting the disease. People with HIV, the Epstein-Barr Virus or who are taking immunosuppressive drugs are at greater risk for some types of lymphoma.

Non-Hodgkin's lymphomas (NHL) are tumors of the peripheral lymph node, thymus, or abnormal organs such as the bowel, but can appear in other sites. These tumors differ substantially from lymphomas seen in adults. In children, NHL may behave similarly to Acute Leukemia in that both cancers can involve bone marrow, blood, skin and the central nervous system. There are approximately 15 types of Non-Hodgkin lymphomas. The distinctions are based on the type of cancer cells.

Therapy varies depending on subtypes and stages of the disease. Chemotherapy and using a combination of drugs, has proven effective. Due to the effectiveness of chemotherapy, there is little role for radiation treatment. Researchers are looking for a better way to refine treatment according to the extent of disease and the tissue subtype.